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Qingkun Ji, Caihong Zhang, Dan Li
《环境科学与工程前沿(英文)》 2020年 第14卷 第6期 doi: 10.1007/s11783-020-1287-0
关键词: Nanofullerene Sub-minimum inhibitory concentrations Antibiotic resistance genes Conjugation Molecular biological techniques
基于消费端的源解析表明不同区域对O<sub>3sub>浓度和健康效应的贡献 Article
Shengqiang Zhu, Peng Wang, Siyu Wang, Guannan Geng, Hongyan Zhao, Yuan Wang, Hongliang Zhang
《工程(英文)》 2023年 第28卷 第9期 页码 130-138 doi: 10.1016/j.eng.2022.11.011
China is confronting aggravated ozone (O3) pollution, leading to adverse health impacts. This study quantifies the regional contributions to O3 in China using two approaches; estimating ① where goods are produced (the production method), and ② where goods are consumed (the consumption method). The production method predicts higher local source contribution than the consumption method; this difference can be attributed to exports. Occurrence of high-O3 episodes suggests a major contribution to O3 concentration as a result of trade activities. Based on the consumption method, 9219 out of 18 532 daily premature mortalities were caused by local sources in north China, while it increased to 14 471 of the production method when neglecting contributions due to export and consumption in other regions. This study suggests that O3 control should consider both where goods are consumed and emissions are emitted, especially taking account of international trade activities.
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《医学前沿(英文)》 2018年 第12卷 第3期 页码 289-300 doi: 10.1007/s11684-017-0550-7
Silver-containing preparations are widely used in the management of skin wounds, but the effects of silver ions on skin wound healing remain poorly understood. This study investigated the effects of silver ions (Ag+) on the proliferation of human skin keratinocytes (HaCaT) and the production of intracellular reactive oxygen species (ROS). After treating HaCaT cells with Ag+and/or the active oxygen scavenger N-acetyl cysteine (NAC), cell proliferation and intracellular ROS generation were assessed using CCK-8 reagent and DCFH-DA fluorescent probe, respectively. In addition, 5-bromo-2-deoxyUridine (BrdU) incorporation assays, cell cycle flow cytometry, and proliferating cell nuclear antigen (PCNA) immunocytochemistry were conducted to further evaluate the effects of sub-cytotoxic Ag+ concentrations on HaCaT cells. The proliferation of HaCaT cells was promoted in the presence of 10−6 and 10−5 mol/L Ag+ at 24, 48, and 72 h. Intracellular ROS generation also significantly increased for 5–60 min after exposure to Ag+. The number of BrdU-positive cells and the presence of PCNA in HaCaT cells increased 48 h after the addition of 10−6 and 10−5 mol/L Ag+, with 10−5 mol/L Ag+ markedly increasing the cell proliferation index. These effects of sub-cytotoxic Ag+ concentrations were repressed by 5 mmol/L NAC. Our results suggest that sub-cytotoxic Ag+ concentrations promote the proliferation of human keratinocytes and might be associated with a moderate increase in intracellular ROS levels. This study provides important experimental evidence for developing novel silver-based wound agents or dressings with few or no cytotoxicity.
关键词: ionic silver human keratinocyte cell proliferation reactive oxygen species active oxygen scavenger NAC
一种融合多特征聚类与神经网络的PM<sub>2.5sub>小时浓度预测新模型及其在中国城市的应用 Article
刘辉, 龙治豪, 段铸, 施惠鹏
《工程(英文)》 2020年 第6卷 第8期 页码 944-956 doi: 10.1016/j.eng.2020.05.009
PM<sub>2.5sub>浓度预测对空气污染物早期预警具有重要意义。本文提出一种改进的PM<sub>2.5sub>浓度多步预测模型,即多特征聚类分解(MCD)-回声状态网络(ESN)-粒子群优化(PSO)混合模型。该模型包括分解预测部分和优化预测部分。在MCD方法中,采用RSAR算法选择重要的空气污染物变量,使用KC算法对所得变量进行聚类,利用EWT算法将PM<sub>2.5sub>浓度序列的聚类结果分解为多个子层。利用我国4个不同城市的真实PM<sub>2.5sub>浓度数据,验证了所提出模型的有效性。实验结果表明,所提出预测模型适用于PM<sub>2.5sub>浓度的多步高精度预测,具有比基准模型更优的预测性能。
关键词: PM<sub>2.5sub>2.5浓度预测 PM<sub>2.5sub>2.5浓度聚类 经验小波分解 多步预测
《机械工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11465-022-0733-z
关键词: grinding minimum quantity lubrication carbon group nanofluid tribological mechanism
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《医学前沿(英文)》 2012年 第6卷 第3期 页码 288-295 doi: 10.1007/s11684-012-0208-4
Tramadol is a potent analgesic. However, the analgesia efficacy of tramadol, particularly its minimum effective dose (MED), is not clear. The aim of this study is to find MED of tramadol for postoperative analgesia in infants. The continual reassessment method (CRM) was performed to find MED. Infants undergoing surgeries were included in the 3 phases of this series. In each phase, 24 participants were allocated a different tramadol dose. Pain intensity was measured by face, legs, activity, cry, consolability (FLACC) measurement at 3-hour intervals. Tramadol was considered ineffective if the FLACC score was higher than 4 in 10 at anytime. In phase 1, seven dose levels were used within the range 0.1–0.4 mg?kg-1·h-1. Phase 1 was insufficient to identify the MED, and we increased the dose to 0.4–0.8 mg?kg-1·h-1 in phase 2. Phase 2 was insufficient to identify the MED. In phase 3, local anesthetic wound infiltration was introduced, and the tramadol dose levels tested were the same as in phase 1. The successful analgesia probability of tramadol 0.4 mg?kg-1?h-1 was 82.1% (95% CI, 0.742–0.925) in phase 1. In phase 2, it was 84.7% (95% CI, 0.789–0.991) with the dose 0.8 mg?kg-1?h-1. Phase 1 and phase 2 were insufficient to identify the MED. In phase 3, the successful analgesia probability for dose 0.35 mg?kg-1?h-1was 96.7% (95% CI, 0.853–0.997).We have demonstrated that tramadol provides insufficient analgesia for surgeries considered to cause moderate-to-severe postoperative pain in infants if used as the sole analgesic, and that local anesthetic wound infiltration enhances the efficacy of tramadol.
关键词: tramadol minimum effective dose postoperative analgesia infants continual reassessment method
Vanadium and molybdenum concentrations in particulate from Palermo (Italy): analytical methods using
Diana AMORELLO,Santino ORECCHIO
《环境科学与工程前沿(英文)》 2015年 第9卷 第4期 页码 605-614 doi: 10.1007/s11783-014-0703-8
Cryogenic minimum quantity lubrication machining: from mechanism to application
《机械工程前沿(英文)》 2021年 第16卷 第4期 页码 649-697 doi: 10.1007/s11465-021-0654-2
关键词: cryogenic minimum quantity lubrication (CMQL) cryogenic medium processing mode device application mechanism application effect
Jing TENG, Xiaoqian HU, Ningping TAO, Mingfu WANG
《农业科学与工程前沿(英文)》 2018年 第5卷 第3期 页码 321-329 doi: 10.15302/J-FASE-2017182
As one of the dominant reactions occurring during thermal treatment of food, the Maillard reaction not only leads to the formation of aroma, browning color and taste compounds, but also contributes to the formation of some unpleasant toxic substances including acrylamide, heterocyclic amines and advanced glycation end products. Polyphenols, one of the most abundant antioxidants in the human diet, are contained in different kinds of foods. In this review, some recent studies on the impact of dietary polyphenols on the formation of acrylamide, heterocyclic amines and advanced glycation end products formed during the Maillard reaction are summarized, including the research work conducted with both chemical model systems and real food model systems; the possible inhibitory mechanisms of different polyphenols are also summarized and discussed in this review. Basically we found that some dietary polyphenols not only scavenge free radicals, but also react with reactive carbonyl species, thus lowering the formation of toxic Maillard reaction products. This review provides a useful theoretical foundation for the application of polyphenols in food safety, and suggests some directions for further study of natural products as inhibitors against the formation of toxic substances in thermally processed food.
关键词: advanced glycation end products acrylamide food safety heterocyclic amine Maillard reaction polyphenols
Mass concentrations and temporal profiles of PM
Liu YANG,Ye WU,Jiaqi LI,Shaojie SONG,Xuan ZHENG,Jiming HAO
《环境科学与工程前沿(英文)》 2015年 第9卷 第4期 页码 675-684 doi: 10.1007/s11783-014-0731-4
关键词: particulate matter traffic control measure Beijing Olympic Games
Design of a cyclic inhibitory CPG controller for the locomotion of a snakelike robot
LU Zhen-li, MA Shu-gen, LI Bin, WANG Yue-chao
《机械工程前沿(英文)》 2006年 第1卷 第4期 页码 396-402 doi: 10.1007/s11465-006-0046-7
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《机械工程前沿(英文)》 2014年 第9卷 第3期 页码 281-294 doi: 10.1007/s11465-014-0307-9
In this study, the stress concentration factors (SCF) in cross-and-angle-ply laminated composite plates as well as in isotropic plates with single circular holes subjected to uniaxial loading is studied. A quadrilateral finite element of four-node with 32 degrees of freedom at each node, previously developed for the bending and mechanical buckling of laminated composite plates, is used to evaluate the stress distribution in laminated composite plates with central circular holes. Based up on the classical plate theory, the present finite element is a combination of a linear isoparametric membrane element and a high precision rectangular Hermitian element. The numerical results obtained by the present element compare favorably with those obtained by the analytic approaches published in literature. It is observed that the obtained results are very close to the reference results, which demonstrates the accuracy of the present element. Additionally, to determine the first ply failure (FPF) of laminated plate, several failure criterions are employed. Finally, to show the effect of ratio on the failure of plates, a number of figures are given for different fiber orientation angles.
关键词: laminated composite plates stress concentration geometric singularity anisotropic effect
Design, synthesis and HIV-RT inhibitory activity of novel thiazolidin-4-one derivatives
Hua CHEN, Zaihong GUO, Qingmei YIN, Xiaoxu DUAN, Yunjing GU, Xiaoliu LI
《化学科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 231-237 doi: 10.1007/s11705-010-1022-7
关键词: 5-subsituted thiazolidin-4-ones Pummerer reaction anti-HIV-RT activity SARs
Modeling of the minimum cutting thickness in micro cutting with consideration of the friction around
Tianfeng ZHOU, Ying WANG, Benshuai RUAN, Zhiqiang LIANG, Xibin WANG
《机械工程前沿(英文)》 2020年 第15卷 第1期 页码 81-88 doi: 10.1007/s11465-019-0561-y
关键词: tool friction minimum cutting thickness finite element method tool edge radius micro cutting
Achieving air pollutant emission reduction targets with minimum abatement costs: An enterprise-level
《环境科学与工程前沿(英文)》 2022年 第16卷 第2期 doi: 10.1007/s11783-021-1459-6
• Quantification of efficiency and fairness of abatement allocation are optimized.
关键词: Pollutant emission reduction allocation Emission reduction measures Total abatement cost Economic efficiency Abatement space
标题 作者 时间 类型 操作
Influences and mechanisms of nanofullerene on the horizontal transfer of plasmid-encoded antibiotic resistance genes between
Qingkun Ji, Caihong Zhang, Dan Li
期刊论文
基于消费端的源解析表明不同区域对O<sub>3sub>浓度和健康效应的贡献
Shengqiang Zhu, Peng Wang, Siyu Wang, Guannan Geng, Hongyan Zhao, Yuan Wang, Hongliang Zhang
期刊论文
Sub-cytotoxic concentrations of ionic silver promote the proliferation of human keratinocytes by inducing
null
期刊论文
Tribological mechanism of carbon group nanofluids on grinding interface under minimum quantity lubrication
期刊论文
Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the
null
期刊论文
Vanadium and molybdenum concentrations in particulate from Palermo (Italy): analytical methods using
Diana AMORELLO,Santino ORECCHIO
期刊论文
Impact and inhibitory mechanism of phenolic compounds on the formation of toxic Maillard reaction products
Jing TENG, Xiaoqian HU, Ningping TAO, Mingfu WANG
期刊论文
Mass concentrations and temporal profiles of PM
Liu YANG,Ye WU,Jiaqi LI,Shaojie SONG,Xuan ZHENG,Jiming HAO
期刊论文
Design of a cyclic inhibitory CPG controller for the locomotion of a snakelike robot
LU Zhen-li, MA Shu-gen, LI Bin, WANG Yue-chao
期刊论文
Finite element analysis of stress concentrations and failure criteria in composite plates with circular
null
期刊论文
Design, synthesis and HIV-RT inhibitory activity of novel thiazolidin-4-one derivatives
Hua CHEN, Zaihong GUO, Qingmei YIN, Xiaoxu DUAN, Yunjing GU, Xiaoliu LI
期刊论文
Modeling of the minimum cutting thickness in micro cutting with consideration of the friction around
Tianfeng ZHOU, Ying WANG, Benshuai RUAN, Zhiqiang LIANG, Xibin WANG
期刊论文